PFE

Pfizer Inc. PFE logo
NYSE Healthcare
$28.81
-0.27 (-0.93%)
Updated: 9/3/2026, 8:55:01 PM
Open
$29.09
High
$29.20
Low
$28.45
Prev Close
$29.02
Volume
20.95M

Price History

Why Is PFE ▼ Down Today?

-0.93%

Pfizer shares dip slightly, underperforming sector's positive trend

Pfizer (PFE) shares closed down 0.93% today, contrasting with a modest gain in the overall sector. Despite recent positive coverage on its oncology pipeline and past earnings performance, no specific company-related news appears to have driven today's slight decline.

Key Drivers

Sector underperformance
Pfizer's stock declined while the sector average saw a positive change, indicating company-specific pressure or a lack of catalysts to match sector momentum.

Generated by Highly Regarded's proprietary market analysis engine. Not financial advice.

Financial Highlights

Income Statement

Revenue
$62.78B
Gross Profit
$46.08B
73.4% margin
Operating Income
$9.15B
14.6% margin
Net Income
$9.87B
15.7% margin
EPS (Diluted)
$1.72

Balance Sheet

Total Assets
$208.73B
Total Liabilities
$115.64B
Stockholders' Equity
$93.10B

Cash Flow

Operating Cash Flow
$13.08B
Investing Activities
$3.17B
Net Cash Flow
$242.0M

Highly Regarded Analysis

Updated Sep 3, 2026 • Refreshes daily
Rating
HODL
Risk
Medium
Target
$28.46
Type
Standard

Executive Summary

Pfizer Inc. is a global biopharmaceutical company engaged in the discovery, development, manufacturing, marketing, sale, and distribution of biopharmaceutical products worldwide. The company is currently navigating a period of significant transition, marked by declining sales of its COVID-19 related products and upcoming patent expirations for key revenue-generating drugs like Eliquis, Prevnar, and Ibrance by 2030. To counteract these headwinds, Pfizer is aggressively pursuing new growth avenues through strategic acquisitions, a robust pipeline focused on oncology and obesity, and an extensive cost-cutting program. Recent quarterly results showed beats on both revenue and earnings, driven by non-COVID sales and new product launches, signaling some positive momentum. However, high debt levels and mixed analyst sentiment contribute to a nuanced outlook.

Bull Case

The bull case for Pfizer hinges on the successful execution of its pipeline strategy, particularly in oncology and obesity, with the potential for several new blockbuster drugs by 2030. Aggressive cost-cutting measures are expected to yield substantial operational savings, enhancing future earnings. The company's recent Q2 2026 earnings beat, driven by non-COVID product growth, demonstrates its ability to generate sales from new and acquired assets. Continued positive developments and approvals for new vaccines, such as the XFG-adapted COVID-19 vaccine and the Lyme disease vaccine candidate, could further boost revenue. Strategic collaborations and a diversified portfolio position Pfizer for long-term growth as it moves past patent cliffs.

Bear Case

The bear case centers on the significant impact of upcoming patent expirations for major revenue drivers such as Eliquis, Prevnar, and Ibrance, which could lead to substantial revenue declines and create a $1.5 billion headwind, potentially swelling to $4.5 billion in 2027. A sustained decrease in sales of COVID-19 related products, like Paxlovid and Comirnaty, also poses a challenge. High debt levels could limit financial flexibility and increase interest expenses. Furthermore, intense competition from generics and biosimilars, along with potential setbacks in the development or commercialization of pipeline drugs, could hinder future growth and investor sentiment.

Technical Outlook

Pfizer (PFE) is currently in a rising trend channel in the medium term, indicating increasing buy interest. The stock has a positive volume balance, suggesting higher trading volume on days with rising prices. Multiple moving averages (10-day, 20-day, 50-day, 100-day, 200-day exponential and simple) are generating buy signals, suggesting a bullish setup. However, the Relative Strength Index (RSI) is above 70, indicating the stock may be overbought, which could lead to a downward reaction. The stock is also testing a resistance level at $28.60, which could result in a negative reaction if not breached. Some indicators, such as the MACD and CCI, provide mixed or sell signals. Overall, the technical outlook suggests strong recent bullish momentum, but with signs of being overbought and approaching resistance.

Fundamental Health

Pfizer exhibits strong gross and operating margins, indicating efficient core operations and profitability. The company also offers an attractive dividend yield, currently between 5.93% and 6.02%. However, a key weakness is a relatively high level of debt in proportion to its EBITDA. Over the last 12 months, analysts have frequently downgraded EPS expectations, and the company's earnings releases sometimes do not meet expectations. While recent Q2 2026 results exceeded revenue and EPS estimates, driven by non-COVID sales and launched products, a declining trend in operating margin, net margin, Return on Invested Capital (ROIC), and Return on Equity (ROE) has been observed over the past three years. The stock's current Price-to-Earnings (P/E) ratio of 38.43 is significantly higher than the industry average, and intrinsic value analysis suggests the stock may be overvalued by approximately 20%.

Key Catalysts

  • FDA approval for Padcev + Keytruda regimen for cisplatin-eligible muscle-invasive bladder cancer (expected August 2026).
  • Advancement and successful clinical trial readouts for obesity drug candidates (e.g., berobenatide) and oncology pipeline assets (e.g., PF-08634404, Mevrometostat).
  • Realization of substantial savings from the expanded cost realignment program, targeting $9.7 billion in operational savings by 2029.

This analysis was conducted by Highly Regarded's proprietary market analysis engine. It is not financial advice. Always do your own research and consult a financial advisor before making investment decisions.

Go Deeper on PFE

Key Stats

P/E Ratio 16.8x
EPS (Diluted) $1.72
Gross Margin 73.4%
Operating Margin 14.6%
Net Margin 15.7%
Revenue (Qtr) $62.78B
Shares Outstanding 5.69B

Next Earnings

Date Nov 3, 2026
Time Before Open
Quarter Q3 2026
EPS Estimate $0.77

PFE News

No recent news for PFE.